Political culture, understood as a constructed set of core values, attitudes and practices shared by a decisive majority of citizens and pervading the political system, has been recognized as a potent factor in framing issues and informing decisions in both domestic and foreign policy. Greek political culture is analyzed on the basis of quantitative evidence and discourse analysis in order to account for trends and choices that affected the country’s relations with the United States, Western Europe and neighboring states during the first post-war decades. Greek-American relations and the Cyprus Question serve as major points of departure.